2021

Yang W*, He H*, Wang T, Su N, Zhang F, Jiang K, Zhu J, Zhang C, Niu K, Wang L, Yuan X, Liu N, Li L, Wei W, Hu J. Single-cell transcriptomic analysis reveals a hepatic stellate cell-activation roadmap and myofibroblast origin during liver fibrosisHepatology. DOI:10.1002/hep.31987. (2021). (*,  co-first authors).

Gengenbacher N*, Singhal M*, Mogler C, Hai L, Milde L, Pari A, Besemfelder E, Fricke C, Baumann D, Gehrs S, Utikal J, Felcht M, Hu J, Schlesner M, Offringa M, Chintharlapalli S, Augustin H. Timed Ang2-Targeted Therapy Identifies the Angiopoietin-Tie Pathway as Key Regulator of Fatal Lymphogenous MetastasisCancer Discovery. 11: 424–445. (2021). (*,  co-first authors).

 

2020

Dai J, Zhang C, Guo L, He H, Kai J, Huang Y, Zhang X, Zhang H, Wei W, Zhang Y, Lu L#, Hu J#. A necroptotic-independent function of MLKL in regulating endothelial cell adhesion molecule expressionCell Death and Disease. 11: 282 (2020). (#,  co-corresponding authors).

Jiang H, Zhang L, Liu X, Sun W, Kato K, Chen C, Li X, Li T, Sun Z, Han W, Zhang H, Xiao Q, Yang Z, Hu J, Qin Z, Adams R, Gao X, He Y. Angiocrine FSTL1 (Follistatin-Like Protein 1) Insufficiency Leads to Atrial and Venous Wall Fibrosis via SMAD3 ActivationArteriosclerosis, Thrombosis, and Vascular Biology. 40: 958972. (2020).

 

2018

Singhal M*Liu X*, Inverso D, Jiang K, Dai J, He H, Bartels S, Li W, Abdul Pari AA, Gengenbacher N, Besemfelder E, Hui L, Augustin H#, Hu J#. Endothelial cell fitness dictates the source of regenerating liver vasculatureJournal of Experimental Medicine. 215: 24972598. (2018). (*,  co-first authors; #,  co-corresponding authors).

Hu C*, Li W*, Tian F, Jiang K, Liu X, Cen J, He Q, Qiu Z, Keenest Y, Wang Z, Zhang H, Ji Y#, Hu J#, Hui L#. Arid1a regulates response to anti-angiogenic therapy in advanced hepatocellular carcinomaJournal of Hepatology. 68: 465–475. (2018). (*,  co-first authors; #,  co-corresponding authors).

Guo L, Yang W, Huang Q, Qiang J, Hart JR, Wang W, Hu J, Zhu J, Liu N, and Zhang Y. Selenocysteine-Specific Mass Spectrometry Reveals Tissue-Distinct Selenoproteomes and Candidate SelenoproteinsCell Chemical Biology. 25: 19. (2018).

 

2017

Manavski Y, Abel T, Hu J, Kleinlützum D, Buchholz CJ, Belz C, Augustin H, Boon R, Dimmeler S. Endothelial transcription factor KLF2 negatively regulates liver regeneration via induction of activin AProceedings of the National Academy of Sciences. 114: 3993–3998. (2017).

Teichert M, Milde L, Holm A, Stanicek L, Gengenbacher N, Savant S, Ruckdeschel T, Hasanov Z, Srivastava K, Hu J, Hertel S, Bartol A, Schlereth K, Augustin H. Pericyte-expressed Tie2 controls angiogenesis and vessel maturationNature Communications. 8, 16106. (2017).

 

2016

SY, Lee JH, Kim SJ, Kim HC, Kim S, Kim SH, Kim C, Nakaoka Y, He Y, Augustin H, Hu J, Song PH, Kim YI, Kim P, Kim I, Koh GY. Amelioration of sepsis by TIE2 activation-induced vascular protectionScience Translational Medicine. 8, 335ra55. (2016).

 

2015

Yang W-J*, Hu J*, Uemura A, Tetzlaff F, Augustin HG, Fischer A. Semaphorin-3C signals through Neuropilin-1 and PlexinD1 receptors to inhibit pathological angiogenesisEMBO Molecular Medicine. 7: 1267–1284. (2015). (*, co-first authors).

Mogler C, Wieland M, König C, Hu J, Runge A, Korn C, Besemfelder E, Breitkopf-Heinlein K, Komljenovic D, Dooley S, Schirmacher P, Longerich T, Augustin H. Hepatic stellate cell-expressed endosialin balances fibrogenesis and hepatocyte proliferation during liver damageEMBO Molecular Medicine. 7: 332–338. (2015).

Savant S, La Porta S, Budnik A, Busch K, Hu J, Tisch N, Korn C, Valls AF, Benest AV, Terhardt D, Qu X, Adams R, Baldwin S, Ruiz de Almodovar C, Rodewald H, Augustin H. The Orphan Receptor Tie1 Controls Angiogenesis and Vascular Remodeling by Differentially Regulating Tie2 in Tip and Stalk CellsCell Reports. 12, 1761–1773. (2015)

 

2014

Srivastava K*, Hu J*, Korn C, Savant S, Teichert M, Kapel S, Jugold M, Besemfelder E, Thomas, M, Pasparakis M, Augustin H. Postsurgical Adjuvant Tumor Therapy by Combining Anti-Angiopoietin-2 and Metronomic Chemotherapy Limits Metastatic GrowthCancer Cell. 26: 880–895. (2014). (*, co-first authors).

Runge A, Hu J, Wieland M, Bergeest J-P, Mogler C, Neumann A, Geraud C, Arnold B, Rohr K, Komljenovic D, Schirmacher P, Goerdt S, Augustin H. An inducible hepatocellular carcinoma model for preclinical evaluation of antiangiogenic therapy in adult miceCancer Research. 74: 4157–4169. (2014).

Korn C*, Scholz B*, Hu J, Srivastava K, Wojtarowicz J, Arnsperger T, Adams R, Boutros M, Augustin H, Augustin I. Endothelial cell-derived non-canonical Wnt ligands control vascular pruning in angiogenesisDevelopment. 141: 1757–1766. (2014).

Hu J*, Srivastava K*, Wieland M, Runge A, Mogler C, Besemfelder E, Terhardt D, Vogel M, Cao L, Korn C, Bartels S, Thomas M, Augustin H. Endothelial cell-derived angiopoietin-2 controls liver regeneration as a spatiotemporal rheostatScience. 343: 416–419. (2014). (*, co-first authors).